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Desmin (Thr76 + Thr77) Antibody, Biotin Conjugated

Desmin (Thr76 + Thr77) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Desmin (Thr76 + Thr77) Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDesmin Thr76 + Thr77
SpecificityThis is a highly specific antibody against Desmin Thr76 + Thr77
ModificationPhosphorylation
Modification siteThr76 + Thr77
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human DES around the phosphorylation site of Thr76/Thr77
Gene ID number1674
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A desmin related myopathy can have a distal onset, Antidesmin are useful in identification of tumours of myogenic origin, CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function, CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I), Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM), In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells, arrhythmias, it is then known as hereditary distal myopathy (HDM), restrictive heart failure, filaments found in muscle cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms CMD1I, CSM1, CSM2, DES, DESM_HUMAN, Desmin, Desmin phospho Thr76+Thr77, Desmin phospho Thr76/Thr77, FLJ12025, FLJ12025, FLJ39719, FLJ39719, FLJ41013, FLJ41013, FLJ41793, FLJ41793, Intermediate filament protein, OTTHUMP00000064865, p-Desmin Thr76/Thr77, Desmin phospho T76/77
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene DSM1 and DSM2 play an important role in Desminopathy, Desmin regulated Myofibrilate Myopathy is a protein filament mutation of muscle proteins, Desmins or DES proteins detect by anti-desmin antibodies and DES ELISA kits
Gene targetDesmin (Thr76 + Thr77) Conjugated
Short name Conjugated, Desmin (Thr76 + Thr77) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Desmin (Thr76 and Thr77) (Antibody to)
Alternative techniqueantibodies

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