Name : Desmin (Thr76 + Thr77) Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN3395742832
| Long name | Cy3 Conjugated, Desmin (Thr76 + Thr77) Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Desmin Thr76 + Thr77 |
| Specificity | This is a highly specific antibody against Desmin Thr76 + Thr77 |
| Modification | Phosphorylation |
| Modification site | Thr76 + Thr77 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human DES around the phosphorylation site of Thr76/Thr77 |
| Gene ID number | 1674 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A desmin related myopathy can have a distal onset, Antidesmin are useful in identification of tumours of myogenic origin, CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function, CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I), Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM), In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells, arrhythmias, it is then known as hereditary distal myopathy (HDM), restrictive heart failure, filaments found in muscle cells |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | CMD1I, CSM1, CSM2, DES, DESM_HUMAN, Desmin, Desmin phospho Thr76+Thr77, Desmin phospho Thr76/Thr77, FLJ12025, FLJ12025, FLJ39719, FLJ39719, FLJ41013, FLJ41013, FLJ41793, FLJ41793, Intermediate filament protein, OTTHUMP00000064865, p-Desmin Thr76/Thr77, Desmin phospho T76/77 |
| Properties | 1 of the Desmin (Thr76 + Thr77) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene | DSM1 and DSM2 play an important role in Desminopathy, Desmin regulated Myofibrilate Myopathy is a protein filament mutation of muscle proteins, Desmins or DES proteins detect by anti-desmin antibodies and DES ELISA kits |
| Gene target | Desmin (Thr76 + Thr77) Conjugated |
| Short name | Conjugated, Desmin (Thr76 + Thr77) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, Desmin (Thr76 and Thr77) (Antibody to) |
| Alternative technique | antibodies |