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DHRS2 Antibody

DHRS2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDHRS2 Primary Polyclonal Antibody
Also known asDHRS2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDHRS2
SpecificityThis is a highly specific antibody against DHRS2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range125-150/258
Subcellular location Mitochondrion, Nucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DHRS2
Gene ID number10202
Swiss ProtQ13268
Tested Applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 2, Attenuates MDM2-mediated p53/TP53 degradation, No reductase activity is displayed in vitro with steroids, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21, retinoids and sugars as substrates, 2-propanedione as substrates, 3-Heptanedione and 1-Phenyl-1, 4-Hexanedione, Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DHRS2, Dehydrogenase/reductase SDR family member 2, Dicarbonyl reductase HEP27, Protein D, SDR25C1, mitochondrial, HEP27
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDHRS2
Short nameDHRS2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namedehydrogenase/reductase (SDR family) member 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DHRS2 and IDBG-3407 and ENSG00000100867 and 10202, Dhrs2 and IDBG-163262 and ENSMUSG00000022209 and 71412, HEP27 and SDR25C1, nuclei, oxidoreductase activity, this GO :0004090 and carbonyl reductase (NADPH) activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0008152 and metabolic process and biological process this GO :0008207 and C21-steroid hormone metabolic process and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009636 and response to toxic substance and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0034599 and cellular response to oxidative stress and biological process this GO :0043011 and myeloid dendritic cell differentiation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004090: carbonyl reductase (NADPH) activity, this GO :0004090: carbonyl reductase (NADPH) activity and also this GO :0016491: oxidoreductase activity, this GO :0016491: oxidoreductase activity, dehydrogenase/reductase (SDR family) member 2
Identity 18349
Gene DHRS2
Long gene name dehydrogenase/reductase 2
Synonyms gene name dehydrogenase/reductase (SDR family) member 2
Synonyms HEP27 SDR25C1
Synonyms name member 1 , short chain dehydrogenase/reductase family 25C
Locus 14q11, 2
Discovery year 2002-04-26
Entrez gene record 10202
Pubmed identfication 7556196 11944995 16685466 19027726
RefSeq identity NM_182908
Classification Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT OTTHUMG00000028771

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