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DIAPH1 Antibody

DIAPH1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDIAPH1 Primary Polyclonal Antibody
Also known asDIAPH1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDIAPH1
SpecificityThis is a highly specific antibody against DIAPH1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DIAPH1
Gene ID number1729
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization, DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics, Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration (By similarity), Has neurite outgrowth promoting activity (By similarity), In hear cells, In turn, It controls the localization of APC and CLASP2 to the cell membrane, Nucleates actin filaments, Required for cytokinesis, Required for the assembly of F-actin structures, The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex, and transcriptional activation of the serum response factor, it may play a role in the regulation of actin polymerization in hair cells, membrane-bound APC allows the localization of the MACF1 to the cell membrane, such as actin cables and stress fibers, via the regulation of GSK3B activity, which is required for microtubule capture and stabilization, Acts in a Rho-dependent manner to recruit PFY1 to the membrane
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DFNA1, DIAP1, DIAP1_HUMAN, DIAPH1, DRF1, Deafness autosomal dominant 1, Diaphanous protein homolog 1, Diaphanous related formin 1, Diaphanous-related formin-1, FLJ25265, LFHL1, Protein diaphanous homolog 1, autosomal dominant 1, deafness, diaphanous homolog 1, hDIA1, low frequency hearing loss 1, p140DIA, DIAPH1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDIAPH1
Short nameDIAPH1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDIAPH1 (Antibody to)
Alternative techniqueantibodies
Identity 2876
Gene DIAPH1
Long gene name diaphanous related formin 1
Synonyms gene DFNA1
Synonyms gene name diaphanous (Drosophila, homolog) 1 diaphanous homolog 1 (Drosophila)
Synonyms hDIA1 LFHL1
Locus 5q31, 3
Discovery year 1998-03-17
GenBank acession BC007411
Entrez gene record 1729
Pubmed identfication 9360932 1350680
RefSeq identity NM_005219
Havana BLAST/BLAT OTTHUMG00000149893
Locus Specific Databases Hereditary Hearing Loss Homepage

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