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Dicer Antibody

Dicer Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDicer
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the Dicer antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points
Intented useThis Dicer antibodyis to be used only for research purposes and not for diagnostics
Gene ID #23405
PurityAntigen affinity
Description Dicer also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs, In addition, It is mapped to 14q32, It is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression, The enzyme possesses an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus, The gene, a member of the ribonuclease III (RNaseIII) family, is involved in the generation of microRNAs (miRNAs), it is required for formation of the RNA induced silencing complex (RISC), which modulate gene expression at the posttranscriptional level, 13, Dicer is an enzyme that in humans is encoded by the DICER1 gene
ImmunogenHuman partial recombinant protein (AA 1-195) was used as the immunogen for this Dicer antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Dicer antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDicer
Short nameDicer Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDicer (Antibody to)
Alternative techniqueantibodies
Identity 7184
Gene MNG1
Long gene name dicer 1, ribonuclease III
Synonyms gene name Dcr-1 homolog (Drosophila) multinodular goitre 1 dicer 1, Dicer1, ribonuclease type III
Synonyms Dicer KIAA0928 K12H4, 8-LIKE HERNA DICER1
Synonyms name dicer 1, double-stranded RNA-specific endoribonuclease
Locus 14q32, 13
Discovery year 2002-05-09
GenBank acession AB028449
Entrez gene record 23405
Pubmed identfication 10051563 10786632 21205968
Classification RNA helicases
Havana BLAST/BLAT OTTHUMG00000166134
Locus Specific Databases LRG_492

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