Name : DIS3L Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5330976339
| Long name | ALEXA FLUOR 488 Conjugated, DIS3L Polyclonal Antibody |
| Also known as | Anti-DIS3L PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DIS3L |
| Specificity | This is a highly specific antibody against DIS3L |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DIS3L |
| Gene ID Number | 115752 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Abnormal expression levels of DIS3 may be associated with colon cancer, DIS3, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, Multiple isoforms of DIS3 exist due to alternative splicing events, The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3â, Widely expressed with highest expression in testis, also known as RRP44, exoribonucleases, for proper mitotic progression, is a 958 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one PINc domain, regions, some of which are 3â, suggesting a role for DIS3 in tumorigenesis, to 5â, ultimately, &euro, &euro, &euro, &trade, &trade, &trade, The exosome is a multi-protein complex composed of several highly conserved subunits |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | MGC4562 FLJ38088 KIAA1955 DIS3L1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DIS3L Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | DIS3L |
| Short name | DIS3L Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, DIS3L (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28698 |
| Gene | DIS3L |
| Long gene name | DIS3 like exosome 3', exoribonuclease , -5' |
| Synonyms gene name | DIS3 mitotic control homolog (S, cerevisiae)-like |
| Locus | 15q22, 31 |
| Discovery year | 2007-01-12 |
| Entrez gene record | 115752 |
| Pubmed identfication | 20531386 |
| RefSeq identity | NM_133375 |
| Classification | Exosome complex |
| Havana BLAST/BLAT | OTTHUMG00000133181 |