Name : DIS3L Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN2716129208
| Long name | Biotin Conjugated, DIS3L Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DIS3L |
| Specificity | This is a highly specific antibody against DIS3L |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human DIS3L |
| Gene ID number | 115752 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Abnormal expression levels of DIS3 may be associated with colon cancer, DIS3, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, Multiple isoforms of DIS3 exist due to alternative splicing events, The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3â, Widely expressed with highest expression in testis, also known as RRP44, exoribonucleases, for proper mitotic progression, is a 958 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one PINc domain, regions, some of which are 3â, suggesting a role for DIS3 in tumorigenesis, to 5â, ultimately, &euro, &euro, &euro, &trade, &trade, &trade, The exosome is a multi-protein complex composed of several highly conserved subunits |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | MGC4562 FLJ38088 KIAA1955 DIS3L1 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DIS3L Conjugated |
| Short name | Conjugated, DIS3L Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, DIS3L (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28698 |
| Gene | DIS3L |
| Long gene name | DIS3 like exosome 3', exoribonuclease , -5' |
| Synonyms gene name | DIS3 mitotic control homolog (S, cerevisiae)-like |
| Locus | 15q22, 31 |
| Discovery year | 2007-01-12 |
| Entrez gene record | 115752 |
| Pubmed identfication | 20531386 |
| RefSeq identity | NM_133375 |
| Classification | Exosome complex |
| Havana BLAST/BLAT | OTTHUMG00000133181 |