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DIS3L Antibody, Biotin Conjugated

DIS3L Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, DIS3L Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDIS3L
SpecificityThis is a highly specific antibody against DIS3L
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DIS3L
Gene ID number115752
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Abnormal expression levels of DIS3 may be associated with colon cancer, DIS3, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, Multiple isoforms of DIS3 exist due to alternative splicing events, The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3â, Widely expressed with highest expression in testis, also known as RRP44, exoribonucleases, for proper mitotic progression, is a 958 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one PINc domain, regions, some of which are 3â, suggesting a role for DIS3 in tumorigenesis, to 5â, ultimately, &euro, &euro, &euro, &trade, &trade, &trade, The exosome is a multi-protein complex composed of several highly conserved subunits
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms MGC4562 FLJ38088 KIAA1955 DIS3L1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDIS3L Conjugated
Short name Conjugated, DIS3L Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, DIS3L (Antibody to)
Alternative techniqueantibodies
Identity 28698
Gene DIS3L
Long gene name DIS3 like exosome 3', exoribonuclease , -5'
Synonyms gene name DIS3 mitotic control homolog (S, cerevisiae)-like
Locus 15q22, 31
Discovery year 2007-01-12
Entrez gene record 115752
Pubmed identfication 20531386
RefSeq identity NM_133375
Classification Exosome complex
Havana BLAST/BLAT OTTHUMG00000133181

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