Name : DISC1 (584CT4.2.1) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN2117924457
| Long name | 1) Monoclonal Antibody, 2, DISC1 (584CT4 |
| Also known as | 1) Monoclonal Antibody, 2, DISC1 (584CT4 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DISC1 |
| Specificity | This is a highly specific antibody against DISC1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1, 2, 584CT4 |
| Source | This DISC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from human DISC1 |
| Gene ID number | 27185 |
| Swiss Prot | Q9NRI5 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100~250) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A, Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance, Plays a role, Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development, Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus, dendritic development and synapse formation, in the microtubule network formation, including neuron positioning, together with PCNT, Involved in the regulation of multiple aspects of embryonic and adult neurogenesis |
| Purification method | This antibody is prepared by Euglobin precipitation followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | C1orf136, DISC1, Disrupted in schizophrenia 1 protein, KIAA0457, SCZD9 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 1) Monoclonal, 2, DISC1 (584CT4 |
| Short name | 1) Monoclonal Antibody, 2, DISC1 (584CT4 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 1) monoclonal (Antibody to), 2, DISC1 (584CT4 |
| Alternative technique | antibodies |
| Identity | 2888 |
| Gene | DISC1 |
| Long gene name | disrupted in schizophrenia 1 |
| Locus | 1q42, 2 |
| Discovery year | 2000-01-20 |
| GenBank acession | AF222980 |
| Entrez gene record | 27185 |
| Pubmed identfication | 10814723 |
| RefSeq identity | NM_018662 |
| Havana BLAST/BLAT | OTTHUMG00000037835 |