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DISC1 Antibody

DISC1 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDISC1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the DISC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis DISC1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9NRI5
PurityAntigen affinity
Description Ma et al, Millar et al, Ozeki et al, and that elevation of cellular cAMP leads to dissociation of PDE4B from DISC1 and in increase in PDE4B activity, implicated in susceptibility to schizophrenia, with the highest levels in late embryonic life during development of the cerebral cortex, (2002) determined that the mouse gene maps to chromosome 8 in a region with homology of synteny to human chromosome 1q42, (2003) demonstrated that rodent Disc1 expression displayed pronounced developmental regulation, (2005) showed that the protein interacts with the UCR2 domain of phosphodiesterase-4B, Disrupted in Schizophrenia 1 is a protein that is encoded by the DISC1 gene in humans
ImmunogenAn amino acid sequence from the N-terminus of human Disrupted in Schizophrenia 1 (EESHHSESRARQCGLDSR) was used as the immunogen for this DISC1 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DISC1 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDISC1
Short nameDISC1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDISC1 (Antibody to)
Alternative techniqueantibodies
Identity 2888
Gene DISC1
Long gene name disrupted in schizophrenia 1
Locus 1q42, 2
Discovery year 2000-01-20
GenBank acession AF222980
Entrez gene record 27185
Pubmed identfication 10814723
RefSeq identity NM_018662
Havana BLAST/BLAT OTTHUMG00000037835

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