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DJ-1 Antibody

DJ-1 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDJ-1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, WB
Recommended dilutionsImmunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the DJ-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis DJ-1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q99497
PurityPurified
Description Defects in Park7/DJ-1 are the cause of autosomal recessive early-onset Parkinson disease 7, It is detected in tau inclusions in brains from neurodegenerative disease patients, Sertoli cells, This protein has been shown to protect neurons against oxidative stress and cell death, a form of Parkinson disease characterized by onset before 40 years, and is generally highly expressed in pancreas, and may function as redox-sensitive chaperone and as sensor for oxidative stress, and to play a role in fertilization, as well as preventing aggregation of SNCA, astrocytes, brain, kidney, liver, skeletal muscle, slow progression and initial good response to levodopa, spermatids and spermatozoa, spermatogonia, testis and heart, with detectable levels in placenta, Park7/DJ-1 acts as positive regulator of androgen receptor-dependent transcription
ImmunogenA portion of amino acids 1-30 from the human protein was used as the immunogen for this DJ-1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DJ-1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDJ-1
Short nameDJ-1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDJ-1 (Antibody to)
Alternative techniqueantibodies
Identity 16369
Gene PARK7
Long gene name Parkinsonism associated deglycase
Synonyms gene name Parkinson disease (autosomal recessive, early onset) 7 parkinson protein 7
Synonyms DJ-1 DJ1
Locus 1p36, 23
Discovery year 2001-08-07
GenBank acession D61380
Entrez gene record 11315
Pubmed identfication 11462174 9070310 25416785
RefSeq identity NM_007262
Classification Parkinson disease associated genes
Havana BLAST/BLAT OTTHUMG00000001210
Locus Specific Databases Parkinson', s disease Mutation Database

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