DLL1 Antibody

DLL1 Antibody size: 0.1mg 389

Price 389

Size 0.1mg

Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit

Category	Antibody
Concentration	2ml sterile DI water, 5mg/ml if reconstituted with 0
Form	Antigen affinity purified
Conjugation	Unconjugated
Clone	Polyclonal antibody
Recognised antigen	DLL1
Host animal	Rabbit (Oryctolagus cuniculus)
Clonality	Polyclonal (rabbit origin)
Species reactivity	Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications	WB
Recommended dilutions	5-1ug/ml, Western blot: 0
Notes	Titration of the DLL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented use	This DLL1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #	O00548
Purity	Antigen affinity
Description	Functional analysis by Han et al, Galceran et al, Gray et al, In contrast, It may play a role in cell-to-cell communication, It plays a role in mediating cell fate decisions during hematopoiesis, JAG1 did not disturb either B-cell or T-cell/NK-cell development, Jaleco et al, The protein is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family, Using FISH, also known as DL1 or DELTA1, and mutation of the Lef1 sites impaired expression of a reporter transgene in the presomitic mesoderm of embryonic mice, found that mouse Lef1 bound multiple sites in the DLL1 promoter in vitro and in vivo, is a protein that in humans is encoded by the DLL1 gene, near a locus for type I diabetes, (1999) mapped the gene to chromosome 6q27, (2000) suggested that a soluble fusion protein containing the DSL domain of DLL1 and its adjacent 50 N-terminal amino acids increased the viability of hemopoietic cells but inhibited cell death, (2001) used a cell coculture assay to show that DLL1 blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor, Delta-like 1
Immunogen	Amino acids 168-184 (RTDLKYSYRFVCDEHYY-human) were used as the immunogen for this DLL1 antibody
Storage	Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DLL1 antibody can be stored for up to one month at 4oC, After reconstitution
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target	DLL1
Short name	DLL1 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	delta-like 1 (Drosophila) (Antibody to)
Alternative technique	antibodies
Alternative to gene target	DLL1 and IDBG-636101 and ENSBTAG00000031476 and 101908771, DLL1 and IDBG-99280 and ENSG00000198719 and 28514, Dll1 and IDBG-139653 and ENSMUSG00000014773 and 13388, Extracellular, protein binding, this GO :0001709 and cell fate determination and biological process this GO :0001756 and somitogenesis and biological process this GO :0001757 and somite specification and biological process this GO :0001947 and heart looping and biological process this GO :0005112 and Notch binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007154 and cell communication and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007220 and Notch receptor processing and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007368 and determination of left/right symmetry and biological process this GO :0007386 and compartment pattern specification and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030154 and cell differentiation and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0032693 and negative regulation of interleukin-10 production and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045608 and negative regulation of auditory receptor cell differentiation and biological process this GO :0045638 and negative regulation of myeloid cell differentiation and biological process this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045747 and positive regulation of Notch signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048839 and inner ear development and biological process this GO :0050767 and regulation of neurogenesis and biological process this GO :0070986 and left/right axis specification and biological process this GO :0072014 and proximal tubule development and biological process this GO :0072070 and loop of Henle development and biological process this GO :0097150 and neuronal stem cell maintenance and biological process, this GO :0005112: Notch binding, this GO :0005112: Notch binding and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, 788775, delta-like 1 (Drosophila)
Identity	2908
Gene	DLL1
Long gene name	delta like canonical Notch ligand 1
Synonyms gene name	delta (Drosophila)-like 1 delta-like 1 (Drosophila)
Locus	6q27
Discovery year	2000-02-11
GenBank acession	AF003522
Entrez gene record	28514
Havana BLAST/BLAT	OTTHUMG00000016078

DLL1 Antibody

DLL1 Antibody size: 0.1mg 389

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