Name : DLP1 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5276158048
| Long name | FITC Conjugated, DLP1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DLP1 |
| Specificity | This is a highly specific antibody against DLP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 50-100/736 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human DNM1L |
| Gene ID number | 10059 |
| Swiss Prot | O00429 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Also required for mitochondrial fission during mitosis, Facilitates developmentally regulated apoptosis during neural tube formation, Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed, Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism, Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, Required for a normal rate of cytochrome c release and caspase activation during apoptosis, Required for formation of endocytic vesicles, Required for normal brain development, Required for programmed necrosis execution, Through its function in mitochondrial division, by suppressing oxidative damage, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, including that of cerebellum, the function may require its recruitment by MFF to clathrin-containing vesicles, this requirement may depend upon the cell type and the physiological apoptotic cues, Functions in mitochondrial and peroxisomal division |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | DLP1, DNM1L, DRP1, DVLP, Dnm1p/Vps1p-like protein, Dymple, Dynamin family member proline-rich carboxyl-terminal domain less, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, Dynamin-related protein 1, HdynIV, Dynamin-1-like protein |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DLP1 Conjugated |
| Short name | FITC Conjugated, DLP1 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, DLP1 (Antibody to) |
| Alternative technique | antibodies |