DMC1 Antibody, Biotin Conjugated

DMC1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, DMC1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	DMC1
Specificity	This is a highly specific antibody against DMC1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human DMC1
Gene ID number	11144
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Additional proteins involved in the pathway include Nibrin and Dmc1, An alternative spliced form of Dmc1, Dmc1 is specifically involved in meiotic recombination, Nibrin, Overexpression of Rad52 confers resistance to ionizing radiation and induces homologous intrachromosomal recombination, Rad51 is essential for mitotic and meiotic recombination, Rad52 is thought to be involved in an early stage of Rad51-mediated recombination, The DNA repair proteins Rad51 and Rad52 are key components of the double-strand-break repair (DSBR) pathway, The alternatively spliced Dmc1-D transcript is detected in both male and female germ cells, and its mutation in yeast and mammalian cells results in chromosome loss, designated Dmc1-D, indicating that the encoded protein may have a role in mammalian genetic recombination in meiosis, is absent in Nijemegen breakage syndrome (NBS) patients, is deleted for a region between the two motifs involved in nucleotide binding, which complexes with Mre11 and Rad50, DNA repair proteins are necessary for the maintenance of chromosome integrity and are involved in the elimination of premutagenic lesions from DNA
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	LIM15
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	DMC1 Conjugated
Short name	Conjugated, DMC1 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, DMC1 (Antibody to)
Alternative technique	antibodies
Identity	2927
Gene	DMC1
Long gene name	DNA meiotic recombinase 1
Synonyms gene name	DMC1 (dosage suppressor of mck1, meiosis-specific homologous recombination (yeast) , yeast homolog) meiosis-specific homologous recombination DMC1 dosage suppressor of mck1 homolog
Locus	22q13, 1
Discovery year	1999-10-29
GenBank acession	D63882
Entrez gene record	11144
Pubmed identfication	8602360 8590282 17541404
RefSeq identity	NM_007068
Havana BLAST/BLAT	OTTHUMG00000151088

DMC1 Antibody, Biotin Conjugated

DMC1 Antibody, Biotin Conjugated size: 0.1ml 333

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