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DMP1 Antibody

DMP1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDMP1 Primary Polyclonal Antibody
Also known asDMP1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDMP1
SpecificityThis is a highly specific antibody against DMP1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DMP1
Gene ID number1758
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen DMP-1 is expressed in bone, DMP-1 is proteolytically processed into N- and C-terminal fragments in the ECM of bone and dentin, DMP-1 is then exported to the extracellular matrix (ECM) where it regulates the nucleation of hydroxyapatite and the formation of calcified tissue, DMP-1 localizes to the nucleus of undifferentiated osteoblasts where it functions as a transcriptional regulator for osteoblast-specific gene activation and induces osteoblast differentiation, DMP-1 undergoes a conformational change and becomes phosphorylated by casein kinase II in response to an influx of calcium ions to the nucleus, During osteoblast maturation, It is important for the mineralization of bone and dentin, It is synthesized by preosteoblasts and contains a large number of acidic domains, The protein has also been identified in bone as a high molecular weight proteoglycan comprised of the N-terminal DMP-1 fragment and chondroitin sulfate, tooth and hypertrophic cartilage, DMP-1 is a member of the small integrin ligand N-linked glycoprotein family, The loss of DMP-1 can result in hypomineralized bone
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ARHR, AV020965, DENTMAT, DMP 1, DMP1_HUMAN, Dentin matrix acidic phosphoprotein 1, Dentin matrix protein 1, Dmp, MGC130441, PP, Serine rich acidic phosphoprotein, ARHP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDMP1
Short nameDMP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namedentin matrix acidic phosphoprotein 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ARHP and ARHR and DMP-1, DMP1 and IDBG-29190 and ENSG00000152592 and 1758, DMP1 and IDBG-643326 and ENSBTAG00000019132 and 281118, Dmp1 and IDBG-185392 and ENSMUSG00000029307 and 13406, extracellular matrix binding, nuclei, this GO :0001503 and ossification and biological process this GO :0005178 and integrin binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0010811 and positive regulation of cell-substrate adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031214 and biomineral tissue development and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0050840 and extracellular matrix binding and molecular function, this GO :0005178: integrin binding, this GO :0005178: integrin binding and also this GO :0005509: calcium ion binding and also this GO :0050840: extracellular matrix binding, this GO :0005509: calcium ion binding, this GO :0050840: extracellular matrix binding, dentin matrix acidic phosphoprotein 1
Identity 2932
Gene DMP1
Long gene name dentin matrix acidic phosphoprotein 1
Synonyms gene name dentin matrix acidic phosphoprotein
Locus 4q22, 1
Discovery year 1995-08-10
GenBank acession U34037
Entrez gene record 1758
Pubmed identfication 8586437 9177774
Classification SIBLING family
Havana BLAST/BLAT OTTHUMG00000130598

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