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DMPK Antibody, ALEXA FLUOR 594

DMPK Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, DMPK Polyclonal Antibody
Also known asAnti-DMPK PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDMPK
SpecificityThis is a highly specific antibody against DMPK
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DMPK
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen DM arises through expansion of CTG repeats in the 3â, DMPK is implicated in myotonic muscular dystrophy (DM), L-type calcium channels, Mutant DMPK transcripts with an extended region of CUG repeats are retained in the nucleus (5), Other substrates for DMPK include myogenin, These transcripts also influence the expression of the DM locus-associated homeodomain protein (DMAHP)/SIX5, an autosomal dominant-inherited disorder that predominately affects skeletal and cardiac muscle and causes defects in cardiac conduction (2, and Phospholemman (PLM) (1), to mediate in part the DM phenotype (6), &euro, &trade, -UTR of the DMPK gene (4), 3), Myotonic dystrophy protein kinase is a multi-domain protein kinase found in muscle that is activated in response to G protein second messengers and proteolysis (1)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms DMK DM1PK MDPK MT-PK
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetDMPK
Short nameDMPK Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, DMPK (Antibody to)
Alternative techniqueantibodies
Identity 2933
Gene DMPK
Long gene name dystrophia myotonica protein kinase
Synonyms gene DM1 DM
Synonyms gene name dystrophia myotonica 1 (includes dystrophia myotonia protein kinase)
Synonyms name dystrophia myotonica 1 DM protein kinase myotonin protein kinase A myotonic dystrophy associated protein kinase thymopoietin homolog
Locus 19q13, 32
Discovery year 1997-10-10
GenBank acession L19268
Entrez gene record 1760
Pubmed identfication 1546325 1546326
RefSeq identity NM_004409
Havana BLAST/BLAT OTTHUMG00000182334

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