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DNA Ligase IV/LIG4 Antibody, ALEXA FLUOR 555

DNA Ligase IV/LIG4 Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, DNA Ligase IV/LIG4 Polyclonal Antibody
Also known asAnti-DNA Ligase IV/LIG4 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDNA Ligase IV/LIG4
SpecificityThis is a highly specific antibody against DNA Ligase IV/LIG4
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range60-110/911
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNA Ligase IV
Gene ID Number3981
Swiss ProtP49917
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends, Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination, The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4, Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetDNA Ligase IV/LIG4
Short nameDNA Ligase IV/LIG4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, Desoxyribonucleic acid, adenosine triphosphate-dependent (Antibody to), Desoxyribonucleic acid Ligase IV/ligase IV
Alternative techniqueantibodies
Alternative to gene target ATP-dependent, DNA, DNA gap filling and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006303 and double-strand break repair via nonhomolo this GO us end joining and biological process this GO :0006310 and DNA recombination and biological process this GO :0007049 and cell cycle and biological process this GO :0007417 and central nervous system development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0010165 and response to X-ray and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0016032 and viral process and biological process this GO :0016874 and ligase activity and molecular function this GO :0032807 and DNA ligase IV complex and cellular component this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033151 and V(D)J recombination and biological process this GO :0033152 and immunoglobulin V(D)J recombination and biological process this GO :0033153 and T cell receptor V(D)J recombination and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045190 and isotype switching and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0050769 and positive regulation of neurogenesis and biological process this GO :0051102 and DNA ligation involved in DNA recombination and biological process this GO :0051103 and DNA ligation involved in DNA repair and biological process this GO :0051276 and chromosome organization and biological process this GO :0051301 and cell division and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0070419 and nonhomolo this GO us end joining complex and cellular component this GO :0071285 and cellular response to lithium ion and biological process this GO :0071897 and DNA biosynthetic process and biological process this GO :0075713 and establishment of integrated proviral latency and biological process, LIG4 and IDBG-49744 and ENSG00000174405 and 3981, LIG4 and IDBG-633610 and ENSBTAG00000015868 and 781252, LIG4S, Lig4 and IDBG-131943 and ENSMUSG00000049717 and 319583, metal ion binding, nuclei, this GO :0000012 and single strand break repair and biological process this GO :0000793 and condensed chromosome and cellular component this GO :0001701 and in utero embryonic development and biological process this GO :0002328 and pro-B cell differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003909 and DNA ligase activity and molecular function this GO :0003910 and DNA ligase (ATP) activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0005958 and DNA-dependent protein kinase-DNA ligase 4 complex and cellular component this GO :0006266 and DNA ligation and biological process this GO :0006273 and lagging strand elongation and biological process this GO :0006281 and DNA repair and biological process this GO :0006297 and nucleotide-excision repair, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003909: DNA ligase activity and also this GO :0003910: DNA ligase (ATP) activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008022: protein C-terminus binding and also this GO :0016874: ligase activity and also this GO :0046872: metal ion binding, this GO :0003909: DNA ligase activity, this GO :0003910: DNA ligase (ATP) activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008022: protein C-terminus binding, this GO :0016874: ligase activity, this GO :0046872: metal ion binding, ligase IV
Identity 6601
Gene LIG4
Long gene name DNA ligase 4
Synonyms gene name ATP-dependent , DNA, ligase IV
Synonyms name polydeoxyribonucleotide synthase [ATP] 4 polynucleotide ligase sealase DNA repair enzyme DNA joinase
Locus 13q33, 3
Discovery year 1995-08-10
GenBank acession X83441
Entrez gene record 3981
Pubmed identfication 7760816
RefSeq identity NM_002312
Classification DNA ligases
Havana BLAST/BLAT OTTHUMG00000017328
Locus Specific Databases LIG4base: Mutation registry for LIG4 syndrome LRG_79

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