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DNA polymerase eta Antibody / POLH

DNA polymerase eta Antibody / POLH size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDNA polymerase eta / POLH
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions1-0, 5ug/ml, Western blot: 0
NotesOptimal dilution of the DNA polymerase eta antibody should be determined by the researcher
Intented useThis DNA polymerase eta antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9Y253
PurityAntigen affinity
Description However, It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases, Mutations in this gene result in XPV, Several transcript variants encoding different isoforms have been found for this gene, This gene encodes a member of the Y family of specialized DNA polymerases, This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination, a variant type of xeroderma pigmentosum, is a protein that in humans is encoded by the POLH gene, it accurately replicates UV-damaged DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, when thymine dimers are present, DNA polymerase eta (POLH)
ImmunogenAmino acids 157-361 of human POLH were used as the immunogen for the DNA polymerase eta antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DNA polymerase eta antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDNA polymerase eta / POLH
Short nameDNA polymerase eta Antibody / POLH
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDesoxyribonucleic acid polymerizing enzyme eta (Antibody to) / POLH
Alternative techniqueantibodies
Identity 9186
Gene POLQ
Long gene name DNA polymerase theta
Synonyms gene name polymerase (DNA directed), theta polymerase (DNA) theta
Synonyms POLH
Locus 3q13, 33
Discovery year 1999-04-15
GenBank acession AF052573
Entrez gene record 10721
Pubmed identfication 10395804
RefSeq identity NM_199420
Classification DNA polymerases
Havana BLAST/BLAT OTTHUMG00000159396

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