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DNA Polymerase iota Antibody

DNA Polymerase iota Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDNA Polymerase iota Primary Polyclonal Antibody
Also known asDNA Polymerase iota PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDNA Polymerase iota
SpecificityThis is a highly specific antibody against DNA Polymerase iota
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNA Polymerase iota
Gene ID number11201
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen At thymine templates, DNA Pol i acts sequentially with DNA Pol Î, DNA Pol i also promotes the replication of damaged DNA by misincorporating deoxynucleotides opposite DNA lesions, DNA Pol i is highly error-prone when replicating undamaged DNA in that it favors the misincorporation of guanine over the correct nucleotide, DNA polymerases can often bypass DNA lesions that block DNA replication, One such DNA polymerase is the distributive enzyme DNA Pol i, POLI is located on human chromosome 18q21, Therefore, a region often implicated in the etiology of many human cancers, adenosine, recombination and mutagenesis, repair, replication involving DNA Pol i is likely to be highly mutagenic, thereby allowing the replication of damaged DNA, to complete the DNA lesion bypass, which is encoded by the POLI gene, which is essential for damage-induced mutagenesis, ©, 2, DNA polymerase activity is essential for replication
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Eta 2, Eta2, POLI, POLI_HUMAN, Polymerase DNA directed iota, RAD 30B, RAD30 homolog B, RAD30B, RAD3OB, DNA polymerase iota
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDNA Polymerase iota
Short nameDNA Polymerase iota Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDesoxyribonucleic acid polymerizing enzyme iota (Antibody to)
Alternative techniqueantibodies
Identity 9815
Gene RAD30B
Long gene name DNA polymerase iota
Synonyms gene RAD3OB
Synonyms gene name polymerase (DNA directed) iota polymerase (DNA) iota
Synonyms POLI
Locus 18q21, 2
Discovery year 2000-01-24
Entrez gene record 11201
Pubmed identfication 17609217
RefSeq identity NM_007195
Classification DNA polymerases
Havana BLAST/BLAT OTTHUMG00000132704

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