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DNA Polymerase iota Antibody, ALEXA FLUOR 594

DNA Polymerase iota Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, DNA Polymerase iota Polyclonal Antibody
Also known asAnti-DNA Polymerase iota PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDNA Polymerase iota
SpecificityThis is a highly specific antibody against DNA Polymerase iota
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNA Polymerase iota
Gene ID Number11201
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen At thymine templates, DNA Pol i acts sequentially with DNA Pol Î, DNA Pol i also promotes the replication of damaged DNA by misincorporating deoxynucleotides opposite DNA lesions, DNA Pol i is highly error-prone when replicating undamaged DNA in that it favors the misincorporation of guanine over the correct nucleotide, DNA polymerases can often bypass DNA lesions that block DNA replication, One such DNA polymerase is the distributive enzyme DNA Pol i, POLI is located on human chromosome 18q21, Therefore, a region often implicated in the etiology of many human cancers, adenosine, recombination and mutagenesis, repair, replication involving DNA Pol i is likely to be highly mutagenic, thereby allowing the replication of damaged DNA, to complete the DNA lesion bypass, which is encoded by the POLI gene, which is essential for damage-induced mutagenesis, ©, 2, DNA polymerase activity is essential for replication
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms POLI
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetDNA Polymerase iota
Short nameDNA Polymerase iota Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Desoxyribonucleic acid polymerizing enzyme iota (Antibody to)
Alternative techniqueantibodies
Identity 9815
Gene RAD30B
Long gene name DNA polymerase iota
Synonyms gene RAD3OB
Synonyms gene name polymerase (DNA directed) iota polymerase (DNA) iota
Locus 18q21, 2
Discovery year 2000-01-24
Entrez gene record 11201
Pubmed identfication 17609217
RefSeq identity NM_007195
Classification DNA polymerases
Havana BLAST/BLAT OTTHUMG00000132704

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