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DNA Polymerase iota Antibody, FITC Conjugated

DNA Polymerase iota Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, DNA Polymerase iota Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDNA Polymerase iota
SpecificityThis is a highly specific antibody against DNA Polymerase iota
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DNA Polymerase iota
Gene ID number11201
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background At thymine templates, DNA Pol i acts sequentially with DNA Pol Î, DNA Pol i also promotes the replication of damaged DNA by misincorporating deoxynucleotides opposite DNA lesions, DNA Pol i is highly error-prone when replicating undamaged DNA in that it favors the misincorporation of guanine over the correct nucleotide, DNA polymerases can often bypass DNA lesions that block DNA replication, One such DNA polymerase is the distributive enzyme DNA Pol i, POLI is located on human chromosome 18q21, Therefore, a region often implicated in the etiology of many human cancers, adenosine, recombination and mutagenesis, repair, replication involving DNA Pol i is likely to be highly mutagenic, thereby allowing the replication of damaged DNA, to complete the DNA lesion bypass, which is encoded by the POLI gene, which is essential for damage-induced mutagenesis, ©, 2, DNA polymerase activity is essential for replication
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms Eta 2, Eta2, POLI, POLI_HUMAN, Polymerase DNA directed iota, RAD 30B, RAD30 homolog B, RAD30B, RAD3OB, DNA polymerase iota
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDNA Polymerase iota Conjugated
Short name FITC Conjugated, DNA Polymerase iota Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Desoxyribonucleic acid polymerizing enzyme iota (Antibody to)
Alternative techniqueantibodies

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