Name : DNAJB6 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7992781892
| Long name | DNAJB6 Primary Polyclonal Antibody |
| Also known as | DNAJB6 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DNAJB6 |
| Specificity | This is a highly specific antibody against DNAJB6 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSJ2/DNAJB6 |
| Gene ID number | 10049 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin, Also reduces cellular toxicity and caspase-3 activity, Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70, Reduces huntingtin aggregation associated with HD, Plays an indispensable role in the organization of KRT8/KRT18 filaments |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DNAJ B6, DNAJB6, DNJB6_HUMAN, DnaJ, DnaJ homolog subfamily B member 6, HHDJ1, HSJ-2, HSJ2, Heat shock protein J2, MRJ, MSJ-1, MSJ1, DJ4 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DNAJB6 |
| Short name | DNAJB6 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | member 6 (Antibody to), subfamily B, DnaJ (Hsp40) homolog |
| Alternative technique | antibodies |
| Alternative to gene target | DJ4 and DnaJ and HHDJ1 and HSJ-2 and HSJ2 and LGMD1D and LGMD1E and MRJ and MSJ-1, DNA-templated and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051082 and unfolded protein binding and molecular function this GO :0051087 and chaperone binding and molecular function this GO :0060710 and chorio-allantoic fusion and biological process this GO :0060715 and syncytiotrophoblast cell differentiation involved in labyrinthine layer development and biological process this GO :0060717 and chorion development and biological process this GO :0090084 and negative regulation of inclusion body assembly and biological process, DNAJB6 and IDBG-50846 and ENSG00000105993 and 10049, Dnajb3 and IDBG-394183 and ENSMUSG00000081984 and 15504, LOC528549 and IDBG-648942 and ENSBTAG00000018756 and 528549, chaperone binding, member 6, nuclei, subfamily B, this GO :0001671 and ATPase activator activity and molecular function this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006457 and protein folding and biological process this GO :0016020 and membrane and cellular component this GO :0030018 and Z disc and cellular component this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031072 and heat shock protein binding and molecular function this GO :0032781 and positive regulation of ATPase activity and biological process this GO :0034504 and protein localization to nucleus and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045109 and intermediate filament organization and biological process this GO :0045892 and negative regulation of transcription, this GO :0001671: ATPase activator activity, this GO :0001671: ATPase activator activity and also this GO :0003677: DNA binding and also this GO :0005515: protein binding and also this GO :0031072: heat shock protein binding and also this GO :0051082: unfolded protein binding and also this GO :0051087: chaperone binding, this GO :0003677: DNA binding, this GO :0005515: protein binding, this GO :0031072: heat shock protein binding, this GO :0051082: unfolded protein binding, this GO :0051087: chaperone binding, 102724007, DnaJ (Hsp40) homolog |
| Identity | 14888 |
| Gene | DNAJB6 |
| Long gene name | DnaJ heat shock protein family (Hsp40) member B6 |
| Synonyms gene | LGMD1D |
| Synonyms gene name | limb girdle muscular dystrophy 1D (autosomal dominant) DnaJ (Hsp40) homolog, member 6 , subfamily B |
| Synonyms | MRJ |
| Locus | 7q36, 3 |
| Discovery year | 2001-03-09 |
| GenBank acession | AB014888 |
| Entrez gene record | 10049 |
| Pubmed identfication | 10319584 9915854 22366786 |
| Classification | DNAJ (HSP40) heat shock proteins |
| Havana BLAST/BLAT | OTTHUMG00000157242 |