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DNase I Antibody, ALEXA FLUOR 647

DNase I Antibody, ALEXA FLUOR 647 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 647 Conjugated, DNase I Polyclonal Antibody
Also known asAnti-DNase I PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDNase I
SpecificityThis is a highly specific antibody against DNase I
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNase I
Gene ID Number1773
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis, A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, DNase I attacks each strand of DNA independently and the cleavage sites are random, DNase I is a Ca2+ and Mg2+ dependant endonuclease, DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides, DNase I is synthesized in the pancreas and stored in zymogen granules, In the form of a bovine pancreatic enzyme preparation, In the presence of Mg ion, It has been used to reduce the viscosity of cystic fibrosis sputum, The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides, and it was the first DNase for which a specific protein inhibitor was characterized, cells susceptible to apoptosis, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA, it was the first DNase to be crystallized, 2 kb long with 9 exons separated by 8 introns, Deoxyribonuclease I gene is approximately 3
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms DNAS1L3 LSD
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the DNase I Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetDNase I
Short nameDNase I Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, DNase I (Antibody to)
Alternative techniqueantibodies
Identity 2959
Gene DNASE1L3
Long gene name deoxyribonuclease 1 like 3
Synonyms gene name deoxyribonuclease I like 3
Synonyms name DNase gamma
Locus 3p14, 3
Discovery year 1997-05-15
GenBank acession AF047354
Entrez gene record 1776
Pubmed identfication 9205125 9714828 14646506
RefSeq identity NM_004944
Havana BLAST/BLAT OTTHUMG00000159153

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