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DNCLI1 Antibody, FITC Conjugated

DNCLI1 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, DNCLI1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDNCLI1
SpecificityThis is a highly specific antibody against DNCLI1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range480-520/523
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human DNCLI1
Gene ID number51143
Swiss ProtQ9Y6G9
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules, Is required for progress throuh the spindle assembly checkpoint, May play a role in binding dynein to membranous organelles or chromosomes, Probably involved in the microtubule-dependent transport of pericentrin, The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores, Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDNCLI1 Conjugated
Short name FITC Conjugated, DNCLI1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, DNCLI1 (Antibody to)
Alternative techniqueantibodies
Identity 18745
Gene DYNC1LI1
Long gene name dynein cytoplasmic 1 light intermediate chain 1
Synonyms gene DNCLI1
Synonyms gene name cytoplasmic, dynein, light intermediate polypeptide 1
Locus 3p22, 3
Discovery year 2002-06-12
GenBank acession AF078849
Entrez gene record 51143
Pubmed identfication 16260502
RefSeq identity NM_016141
Classification Dyneins, cytoplasmic
Havana BLAST/BLAT OTTHUMG00000130750

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