Name : Dnmt1 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8756167861
| Long name | Biotin Conjugated, Dnmt1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Dnmt1 |
| Specificity | This antibody will not recongize isoform 3, This is a highly specific antibody against Dnmt1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 10-60/1616 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from human Dnmt1 |
| Gene ID number | 1786 |
| Swiss Prot | P26358 |
| Tested applications | IHC-P |
| Recommended dilutions | IHC-P(1:100-500) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication, DNA methylation is coordinated with methylation of histones, In association with DNMT3B and via the recruitment of CTCFL/BORIS, It is responsible for maintaining methylation patterns established in development, Mediates transcriptional repression by direct binding to HDAC2, Preferentially methylates hemimethylated DNA, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9, that is essential for epigenetic inheritance, Methylates CpG residues |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | ADCADN, CXXC-type zinc finger protein 9, CXXC9, DNA (cytosine-5)-methyltransferase 1, DNA MTase HsaI, DNA methyltransferase HsaI, DNMT, Dnmt1, HSN1E, M, MCMT, AIM, HsaI |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Dnmt1 Conjugated |
| Short name | Conjugated, Dnmt1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, Dnmt1 (Antibody to) |
| Alternative technique | antibodies |