Filters

Dnmt2 Antibody, Biotin Conjugated

Dnmt2 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, Dnmt2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDnmt2
SpecificityThis is a highly specific antibody against Dnmt2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Dnmt2
Gene ID number1787
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3, DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, Dnmt1 is the most abundant, Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, Dnmt3a and Dnmt3b are encoded by two distinct genes, The Dnmt enzymes are encoded by independent genes, and is likely involved in methylating newly integrated retroviral DNA, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development, and this methylation results in transcriptional repression of the target gene, but both are abundantly expressed in embryonic stem cells, is expressed at substantially lower levels in adult tissues, where they also methylate CpG motifs on DNA, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms DNA 5 cytosine methyltransferase, DNA MTase homolog HsaIIP, DNA cytosine 5 methyltransferase 2, DNA cytosine 5 methyltransferase like protein 2, DNA cytosine-5-methyltransferase-like protein 2, DNA methyltransferase 2, DNA methyltransferase homolog HsaIIP, DmMT 2, DmMT2, Dnmt 2, Dnmt2, M, MHsaIIP, OTTHUMP00000045198, PuMet, RNMT 1, RNMT1, TRDMT 1, TRDMT1, TRDMT_HUMAN, nmt 2, nmt2, tRNA aspartic acid methyltransferase 1, tRNA aspartic acid methyltransferase 1 variant 1, tRNA aspartic acid methyltransferase 1 variant 2, tRNA aspartic acid methyltransferase 1 variant 3, tRNA aspartic acid methyltransferase 1 variant 4, tRNA aspartic acid methyltransferase 1 variant 5, tRNA aspartic acid methyltransferase 1 variant 8, tRNA cytosine 5 methyltransferase, tRNA cytosine38-C5-methyltransferase, HsaIIP, dDNMT
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDnmt2 Conjugated
Short name Conjugated, Dnmt2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Dnmt2 (Antibody to)
Alternative techniqueantibodies

Subscribe to our Newsletter