Name : Dnmt3 Beta Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8412011052
| Long name | Dnmt3 Beta Primary Polyclonal Antibody |
| Also known as | Dnmt3 Beta PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Dnmt3 Beta |
| Specificity | This is a highly specific antibody against Dnmt3 Beta |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1-50/812 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dnmt3 Beta |
| Gene ID number | 1789 |
| Swiss Prot | Q9UBC3 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | DNA methylation is coordinated with methylation of histones, Function as transcriptional corepressor by associating with ZHX1, In association with DNMT1 and via the recruitment of CTCFL/BORIS, Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs, May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation, May preferentially methylates nucleosomal DNA within the nucleosome core region, Seems to be involved in gene silencing (By similarity), involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9, Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DNA (cytosine-5)-methyltransferase 3B, DNA MTase HsaIIIB, DNA methyltransferase HsaIIIB, Dnmt3b, ICF1, M, HsaIIIB, ICF |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Dnmt3 Beta |
| Short name | Dnmt3 Beta Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Dnmt3 b (Antibody to) |
| Alternative technique | antibodies |