Name : Dnmt3 Beta Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9940994081
| Long name | ALEXA FLUOR 488 Conjugated, Dnmt3 Beta Polyclonal Antibody |
| Also known as | Anti-Dnmt3 Beta PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Dnmt3 Beta |
| Specificity | This is a highly specific antibody against Dnmt3 Beta |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1-50/812 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dnmt3 Beta |
| Gene ID Number | 1789 |
| Swiss Prot | Q9UBC3 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | DNA methylation is coordinated with methylation of histones, Function as transcriptional corepressor by associating with ZHX1, In association with DNMT1 and via the recruitment of CTCFL/BORIS, Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs, May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation, May preferentially methylates nucleosomal DNA within the nucleosome core region, Seems to be involved in gene silencing (By similarity), involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9, Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | DNA (cytosine-5)-methyltransferase 3B, DNA MTase HsaIIIB, DNA methyltransferase HsaIIIB, Dnmt3b, ICF1, M, HsaIIIB, ICF |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Dnmt3 Beta Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Dnmt3 Beta |
| Short name | Dnmt3 Beta Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Dnmt3 b (Antibody to) |
| Alternative technique | antibodies |