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Dnmt3 Beta Antibody, Biotin Conjugated

Dnmt3 Beta Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Dnmt3 Beta Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDnmt3 Beta
SpecificityThis is a highly specific antibody against Dnmt3 Beta
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1-50/812
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human Dnmt3 Beta
Gene ID number1789
Swiss ProtQ9UBC3
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background DNA methylation is coordinated with methylation of histones, Function as transcriptional corepressor by associating with ZHX1, In association with DNMT1 and via the recruitment of CTCFL/BORIS, Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs, May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation, May preferentially methylates nucleosomal DNA within the nucleosome core region, Seems to be involved in gene silencing (By similarity), involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9, Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms DNA (cytosine-5)-methyltransferase 3B, DNA MTase HsaIIIB, DNA methyltransferase HsaIIIB, Dnmt3b, ICF1, M, HsaIIIB, ICF
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDnmt3 Beta Conjugated
Short name Conjugated, Dnmt3 Beta Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Dnmt3 b (Antibody to)
Alternative techniqueantibodies

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