Name : Dnmt3 Beta Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN9585941622
| Long name | Cy7 Conjugated, Dnmt3 Beta Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Dnmt3 Beta |
| Specificity | This is a highly specific antibody against Dnmt3 Beta |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 1-50/812 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from human Dnmt3 Beta |
| Gene ID number | 1789 |
| Swiss Prot | Q9UBC3 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | DNA methylation is coordinated with methylation of histones, Function as transcriptional corepressor by associating with ZHX1, In association with DNMT1 and via the recruitment of CTCFL/BORIS, Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs, May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation, May preferentially methylates nucleosomal DNA within the nucleosome core region, Seems to be involved in gene silencing (By similarity), involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9, Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | DNA (cytosine-5)-methyltransferase 3B, DNA MTase HsaIIIB, DNA methyltransferase HsaIIIB, Dnmt3b, ICF1, M, HsaIIIB, ICF |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | Dnmt3 Beta Conjugated |
| Short name | Conjugated, Dnmt3 Beta Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, Dnmt3 b (Antibody to) |
| Alternative technique | antibodies |