Name : Dnmt3 Beta Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN2295421866
| Long name | FITC Conjugated, Dnmt3 Beta Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Dnmt3 Beta |
| Specificity | This is a highly specific antibody against Dnmt3 Beta |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 1-50/812 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from human Dnmt3 Beta |
| Gene ID number | 1789 |
| Swiss Prot | Q9UBC3 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | DNA methylation is coordinated with methylation of histones, Function as transcriptional corepressor by associating with ZHX1, In association with DNMT1 and via the recruitment of CTCFL/BORIS, Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs, May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation, May preferentially methylates nucleosomal DNA within the nucleosome core region, Seems to be involved in gene silencing (By similarity), involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9, Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | DNA (cytosine-5)-methyltransferase 3B, DNA MTase HsaIIIB, DNA methyltransferase HsaIIIB, Dnmt3b, ICF1, M, HsaIIIB, ICF |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Dnmt3 Beta Conjugated |
| Short name | FITC Conjugated, Dnmt3 Beta Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, Dnmt3 b (Antibody to) |
| Alternative technique | antibodies |