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Dnmt3L Antibody, ALEXA FLUOR 555

Dnmt3L Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, Dnmt3L Polyclonal Antibody
Also known asAnti-Dnmt3L PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDnmt3L
SpecificityThis is a highly specific antibody against Dnmt3L
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dnmt3L
Gene ID Number29947
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Additionally, DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family, Dnmt3L does not exhibit DNA methyltransferase activity, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, Localized to the nucleus and expressed at lows levels in thymus, Multiple isoforms of Dnmt3L exist due to alternative splicing events, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints, mediates transcriptional repression, testis and ovary, thereby repressing expression of the target gene, through this interaction, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms MGC1090
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetDnmt3L
Short nameDnmt3L Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, Dnmt3L (Antibody to)
Alternative techniqueantibodies
Identity 2980
Gene DNMT3L
Long gene name DNA methyltransferase 3 like
Synonyms gene name DNA (cytosine-5-)-methyltransferase 3-like
Synonyms name cytosine-5-methyltransferase 3-like protein
Locus 21q22, 3
Discovery year 2000-05-23
GenBank acession AF194032
Entrez gene record 29947
Pubmed identfication 10857753
RefSeq identity NM_013369
Havana BLAST/BLAT OTTHUMG00000086914

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