Name : Dnmt3L Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5589687590
| Long name | ALEXA FLUOR 647 Conjugated, Dnmt3L Polyclonal Antibody |
| Also known as | Anti-Dnmt3L PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Dnmt3L |
| Specificity | This is a highly specific antibody against Dnmt3L |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dnmt3L |
| Gene ID Number | 29947 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Additionally, DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family, Dnmt3L does not exhibit DNA methyltransferase activity, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, Localized to the nucleus and expressed at lows levels in thymus, Multiple isoforms of Dnmt3L exist due to alternative splicing events, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints, mediates transcriptional repression, testis and ovary, thereby repressing expression of the target gene, through this interaction, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | MGC1090 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Dnmt3L Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | Dnmt3L |
| Short name | Dnmt3L Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, Dnmt3L (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2980 |
| Gene | DNMT3L |
| Long gene name | DNA methyltransferase 3 like |
| Synonyms gene name | DNA (cytosine-5-)-methyltransferase 3-like |
| Synonyms name | cytosine-5-methyltransferase 3-like protein |
| Locus | 21q22, 3 |
| Discovery year | 2000-05-23 |
| GenBank acession | AF194032 |
| Entrez gene record | 29947 |
| Pubmed identfication | 10857753 |
| RefSeq identity | NM_013369 |
| Havana BLAST/BLAT | OTTHUMG00000086914 |