Name : DOCK2 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1394490112
| Long name | ALEXA FLUOR 488 Conjugated, DOCK2 Polyclonal Antibody |
| Also known as | Anti-DOCK2 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DOCK2 |
| Specificity | This is a highly specific antibody against DOCK2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 500-550/1830 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DOCK2 |
| Gene ID Number | 1794 |
| Swiss Prot | Q92608 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activates RAC1 and RAC2, May also participate in IL2 transcriptional activation via the activation of RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP, Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | KIAA0209 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DOCK2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | DOCK2 |
| Short name | DOCK2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, dedicator on cytokinesis 2 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DOCK2 and IDBG-57108 and ENSG00000134516 and 1794, DOCK2 and IDBG-628386 and ENSBTAG00000014612 and, Dock2 and IDBG-161694 and ENSMUSG00000020143 and 94176, Plasma membranes, T cell receptor binding, this GO :0001766 and membrane raft polarization and biological process this GO :0001768 and establishment of T cell polarity and biological process this GO :0001771 and immunological synapse formation and biological process this GO :0002277 and myeloid dendritic cell activation involved in immune response and biological process this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006935 and chemotaxis and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0009055 and electron carrier activity and molecular function this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0020037 and heme binding and molecular function this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030675 and Rac GTPase activator activity and molecular function this GO :0030676 and Rac guanyl-nucleotide exchange factor activity and molecular function this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0042098 and T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0042608 and T cell receptor binding and molecular function this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0044351 and macropinocytosis and biological process this GO :0045059 and positive thymic T cell selection and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0046631 and alpha-beta T cell activation and biological process this GO :0046633 and alpha-beta T cell proliferation and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0009055: electron carrier activity and also this GO :0020037: heme binding and also this GO :0030675: Rac GTPase activator activity and also this GO :0030676: Rac guanyl-nucleotide exchange factor activity and also this GO :0042608: T cell receptor binding, this GO :0005488: binding, this GO :0005515: protein binding, this GO :0009055: electron carrier activity, this GO :0020037: heme binding, this GO :0030675: Rac GTPase activator activity, this GO :0030676: Rac guanyl-nucleotide exchange factor activity, this GO :0042608: T cell receptor binding, dedicator of cytokinesis 2 |
| Identity | 2988 |
| Gene | DOCK2 |
| Long gene name | dedicator of cytokinesis 2 |
| Synonyms gene name | dedicator of cyto-kinesis 2 |
| Locus | 5q35, 1 |
| Discovery year | 1998-05-13 |
| GenBank acession | BC016996 |
| Entrez gene record | 1794 |
| RefSeq identity | NM_004946 |
| Havana BLAST/BLAT | OTTHUMG00000130437 |