Name : DOCK2 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4508585173
| Long name | ALEXA FLUOR 647 Conjugated, DOCK2 Polyclonal Antibody |
| Also known as | Anti-DOCK2 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DOCK2 |
| Specificity | This is a highly specific antibody against DOCK2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 500-550/1830 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DOCK2 |
| Gene ID Number | 1794 |
| Swiss Prot | Q92608 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activates RAC1 and RAC2, May also participate in IL2 transcriptional activation via the activation of RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP, Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | KIAA0209 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the DOCK2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | DOCK2 |
| Short name | DOCK2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, dedicator on cytokinesis 2 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DOCK2 and IDBG-57108 and ENSG00000134516 and 1794, DOCK2 and IDBG-628386 and ENSBTAG00000014612 and, Dock2 and IDBG-161694 and ENSMUSG00000020143 and 94176, Plasma membranes, T cell receptor binding, this GO :0001766 and membrane raft polarization and biological process this GO :0001768 and establishment of T cell polarity and biological process this GO :0001771 and immunological synapse formation and biological process this GO :0002277 and myeloid dendritic cell activation involved in immune response and biological process this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006935 and chemotaxis and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0009055 and electron carrier activity and molecular function this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0020037 and heme binding and molecular function this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030675 and Rac GTPase activator activity and molecular function this GO :0030676 and Rac guanyl-nucleotide exchange factor activity and molecular function this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0042098 and T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0042608 and T cell receptor binding and molecular function this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0044351 and macropinocytosis and biological process this GO :0045059 and positive thymic T cell selection and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0046631 and alpha-beta T cell activation and biological process this GO :0046633 and alpha-beta T cell proliferation and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0009055: electron carrier activity and also this GO :0020037: heme binding and also this GO :0030675: Rac GTPase activator activity and also this GO :0030676: Rac guanyl-nucleotide exchange factor activity and also this GO :0042608: T cell receptor binding, this GO :0005488: binding, this GO :0005515: protein binding, this GO :0009055: electron carrier activity, this GO :0020037: heme binding, this GO :0030675: Rac GTPase activator activity, this GO :0030676: Rac guanyl-nucleotide exchange factor activity, this GO :0042608: T cell receptor binding, dedicator of cytokinesis 2 |
| Identity | 2988 |
| Gene | DOCK2 |
| Long gene name | dedicator of cytokinesis 2 |
| Synonyms gene name | dedicator of cyto-kinesis 2 |
| Locus | 5q35, 1 |
| Discovery year | 1998-05-13 |
| GenBank acession | BC016996 |
| Entrez gene record | 1794 |
| RefSeq identity | NM_004946 |
| Havana BLAST/BLAT | OTTHUMG00000130437 |