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DOCK2 Antibody, FITC Conjugated

DOCK2 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, DOCK2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDOCK2
SpecificityThis is a highly specific antibody against DOCK2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range500-550/1830
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human DOCK2
Gene ID number1794
Swiss ProtQ92608
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activates RAC1 and RAC2, May also participate in IL2 transcriptional activation via the activation of RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP, Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms KIAA0209
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDOCK2 Conjugated
Short name FITC Conjugated, DOCK2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, dedicator on cytokinesis 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DOCK2 and IDBG-57108 and ENSG00000134516 and 1794, DOCK2 and IDBG-628386 and ENSBTAG00000014612 and, Dock2 and IDBG-161694 and ENSMUSG00000020143 and 94176, Plasma membranes, T cell receptor binding, this GO :0001766 and membrane raft polarization and biological process this GO :0001768 and establishment of T cell polarity and biological process this GO :0001771 and immunological synapse formation and biological process this GO :0002277 and myeloid dendritic cell activation involved in immune response and biological process this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006935 and chemotaxis and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0009055 and electron carrier activity and molecular function this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0020037 and heme binding and molecular function this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030675 and Rac GTPase activator activity and molecular function this GO :0030676 and Rac guanyl-nucleotide exchange factor activity and molecular function this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0042098 and T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0042608 and T cell receptor binding and molecular function this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0044351 and macropinocytosis and biological process this GO :0045059 and positive thymic T cell selection and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0046631 and alpha-beta T cell activation and biological process this GO :0046633 and alpha-beta T cell proliferation and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0009055: electron carrier activity and also this GO :0020037: heme binding and also this GO :0030675: Rac GTPase activator activity and also this GO :0030676: Rac guanyl-nucleotide exchange factor activity and also this GO :0042608: T cell receptor binding, this GO :0005488: binding, this GO :0005515: protein binding, this GO :0009055: electron carrier activity, this GO :0020037: heme binding, this GO :0030675: Rac GTPase activator activity, this GO :0030676: Rac guanyl-nucleotide exchange factor activity, this GO :0042608: T cell receptor binding, dedicator of cytokinesis 2
Identity 2988
Gene DOCK2
Long gene name dedicator of cytokinesis 2
Synonyms gene name dedicator of cyto-kinesis 2
Locus 5q35, 1
Discovery year 1998-05-13
GenBank acession BC016996
Entrez gene record 1794
RefSeq identity NM_004946
Havana BLAST/BLAT OTTHUMG00000130437

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