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DOCK4 Antibody, Biotin Conjugated

DOCK4 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, DOCK4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDOCK4
SpecificityThis is a highly specific antibody against DOCK4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DOCK4
Gene ID number9732
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background DOCK 4 contains an N-terminal SH3 domain, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, Expressed ubiquitously with highest expression in prostate, Four isoforms of DOCK 4 are expressed due to alternative splicing events, Similar to other DOCK family members, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2, glioma and colorectal carcinomas, implicated in the pathogenesis of various cancers such as ovarian, ovary and skeletal muscle, plays a role in the regulation of adherens junctions between cells, prostate, thus, via this activation, DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FLJ34238 KIAA0716
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDOCK4 Conjugated
Short name Conjugated, DOCK4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, dedicator on cytokinesis 4 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DOCK4 and IDBG-36595 and ENSG00000128512 and 9732, DOCK4 and IDBG-632981 and ENSBTAG00000021182 and 534227, Dock4 and IDBG-136539 and ENSMUSG00000035954 and 238130, Plasma membranes, Rac GTPase binding, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005829 and cytosol and cellular component this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0017124 and SH3 domain binding and molecular function this GO :0030165 and PDZ domain binding and molecular function this GO :0030675 and Rac GTPase activator activity and molecular function this GO :0030971 and receptor tyrosine kinase binding and molecular function this GO :0032420 and stereocilium and cellular component this GO :0032421 and stereocilium bundle and cellular component this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0048365 and Rac GTPase binding and molecular function this GO :0060326 and cell chemotaxis and biological process, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005515: protein binding and also this GO :0017124: SH3 domain binding and also this GO :0030165: PDZ domain binding and also this GO :0030675: Rac GTPase activator activity and also this GO :0030971: receptor tyrosine kinase binding and also this GO :0048365: Rac GTPase binding, this GO :0005515: protein binding, this GO :0017124: SH3 domain binding, this GO :0030165: PDZ domain binding, this GO :0030675: Rac GTPase activator activity, this GO :0030971: receptor tyrosine kinase binding, this GO :0048365: Rac GTPase binding, dedicator of cytokinesis 4
Identity 19192
Gene DOCK4
Long gene name dedicator of cytokinesis 4
Locus 7q31, 1
Discovery year 2003-11-19
Entrez gene record 9732
Pubmed identfication 12432077 12628187
RefSeq identity NM_014705
Havana BLAST/BLAT OTTHUMG00000155077

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