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DOCK5 Antibody

DOCK5 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDOCK5 Primary Polyclonal Antibody
Also known asDOCK5 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDOCK5
SpecificityThis is a highly specific antibody against DOCK5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DOCK5
Gene ID number80005
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen DOCK 5 contains one DHR-1 (CZH-1) domain, Due to siRNA knockdown studies, In mice, The DHR-2 domain is a putative GEF activity mediator, There are two isoforms of DOCK 5 that exist as a result of alternative splicing events, This cytoplasmic peripheral membrane protein activates Rac 1 and Rac 2 small GTPases, it is suspected that DOCK 5 may also be an important mediator of CrkII/CrkL regulation of Caco-2 migration and spreading on COL4, one DHR-2 (CZH-2) domain and one SH3 domain, resulting in rupture of lens cataract (RLC), spontaneous mutation of the gene encoding DOCK 5 leads to deletion of the DHR-1 domain, which exchanges bound GDP for free GTP, which functions to bind phospholipids and assists in protein-protein interactions, while presumably acting as a guanine nucleotide exchange factor (GEF), 870 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins, DOCK 5 is a 1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DKFZp451J181, DKFZp779M164, DKFZp781J211, DOCK5_HUMAN, Dedicator of cytokinesis protein 5, Dock 5, Dedicator of cytokinesis 5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDOCK5
Short nameDOCK5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namededicator on cytokinesis 5 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Cytoplasm, DOCK5 and IDBG-12661 and ENSG00000147459 and 80005, DOCK5 and IDBG-635373 and ENSBTAG00000015513 and 505572, Dock5 and IDBG-176271 and ENSMUSG00000044447 and 68813, protein binding, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0043547 and positive regulation of GTPase activity and biological process, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005488: binding and also this GO :0005515: protein binding, this GO :0005488: binding, this GO :0005515: protein binding, dedicator of cytokinesis 5
Identity 23476
Gene DOCK5
Long gene name dedicator of cytokinesis 5
Synonyms FLJ21034
Locus 8p21, 2
Discovery year 2003-11-19
Entrez gene record 80005
Pubmed identfication 12432077
RefSeq identity NM_024940
Havana BLAST/BLAT OTTHUMG00000131991

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