Name : DOCK5 Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8296428193
| Long name | ALEXA FLUOR 555 Conjugated, DOCK5 Polyclonal Antibody |
| Also known as | Anti-DOCK5 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DOCK5 |
| Specificity | This is a highly specific antibody against DOCK5 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DOCK5 |
| Gene ID Number | 80005 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | DOCK 5 contains one DHR-1 (CZH-1) domain, Due to siRNA knockdown studies, In mice, The DHR-2 domain is a putative GEF activity mediator, There are two isoforms of DOCK 5 that exist as a result of alternative splicing events, This cytoplasmic peripheral membrane protein activates Rac 1 and Rac 2 small GTPases, it is suspected that DOCK 5 may also be an important mediator of CrkII/CrkL regulation of Caco-2 migration and spreading on COL4, one DHR-2 (CZH-2) domain and one SH3 domain, resulting in rupture of lens cataract (RLC), spontaneous mutation of the gene encoding DOCK 5 leads to deletion of the DHR-1 domain, which exchanges bound GDP for free GTP, which functions to bind phospholipids and assists in protein-protein interactions, while presumably acting as a guanine nucleotide exchange factor (GEF), 870 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins, DOCK 5 is a 1 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | FLJ21034 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | DOCK5 |
| Short name | DOCK5 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, dedicator on cytokinesis 5 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Cytoplasm, DOCK5 and IDBG-12661 and ENSG00000147459 and 80005, DOCK5 and IDBG-635373 and ENSBTAG00000015513 and 505572, Dock5 and IDBG-176271 and ENSMUSG00000044447 and 68813, protein binding, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0043547 and positive regulation of GTPase activity and biological process, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005488: binding and also this GO :0005515: protein binding, this GO :0005488: binding, this GO :0005515: protein binding, dedicator of cytokinesis 5 |
| Identity | 23476 |
| Gene | DOCK5 |
| Long gene name | dedicator of cytokinesis 5 |
| Locus | 8p21, 2 |
| Discovery year | 2003-11-19 |
| Entrez gene record | 80005 |
| Pubmed identfication | 12432077 |
| RefSeq identity | NM_024940 |
| Havana BLAST/BLAT | OTTHUMG00000131991 |