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DOCK5 Antibody, Biotin Conjugated

DOCK5 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, DOCK5 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDOCK5
SpecificityThis is a highly specific antibody against DOCK5
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DOCK5
Gene ID number80005
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background DOCK 5 contains one DHR-1 (CZH-1) domain, Due to siRNA knockdown studies, In mice, The DHR-2 domain is a putative GEF activity mediator, There are two isoforms of DOCK 5 that exist as a result of alternative splicing events, This cytoplasmic peripheral membrane protein activates Rac 1 and Rac 2 small GTPases, it is suspected that DOCK 5 may also be an important mediator of CrkII/CrkL regulation of Caco-2 migration and spreading on COL4, one DHR-2 (CZH-2) domain and one SH3 domain, resulting in rupture of lens cataract (RLC), spontaneous mutation of the gene encoding DOCK 5 leads to deletion of the DHR-1 domain, which exchanges bound GDP for free GTP, which functions to bind phospholipids and assists in protein-protein interactions, while presumably acting as a guanine nucleotide exchange factor (GEF), 870 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins, DOCK 5 is a 1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FLJ21034
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDOCK5 Conjugated
Short name Conjugated, DOCK5 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, dedicator on cytokinesis 5 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Cytoplasm, DOCK5 and IDBG-12661 and ENSG00000147459 and 80005, DOCK5 and IDBG-635373 and ENSBTAG00000015513 and 505572, Dock5 and IDBG-176271 and ENSMUSG00000044447 and 68813, protein binding, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0043547 and positive regulation of GTPase activity and biological process, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005488: binding and also this GO :0005515: protein binding, this GO :0005488: binding, this GO :0005515: protein binding, dedicator of cytokinesis 5
Identity 23476
Gene DOCK5
Long gene name dedicator of cytokinesis 5
Locus 8p21, 2
Discovery year 2003-11-19
Entrez gene record 80005
Pubmed identfication 12432077
RefSeq identity NM_024940
Havana BLAST/BLAT OTTHUMG00000131991

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