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DOCK5 Antibody, FITC Conjugated

DOCK5 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, DOCK5 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDOCK5
SpecificityThis is a highly specific antibody against DOCK5
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DOCK5
Gene ID number80005
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background DOCK 5 contains one DHR-1 (CZH-1) domain, Due to siRNA knockdown studies, In mice, The DHR-2 domain is a putative GEF activity mediator, There are two isoforms of DOCK 5 that exist as a result of alternative splicing events, This cytoplasmic peripheral membrane protein activates Rac 1 and Rac 2 small GTPases, it is suspected that DOCK 5 may also be an important mediator of CrkII/CrkL regulation of Caco-2 migration and spreading on COL4, one DHR-2 (CZH-2) domain and one SH3 domain, resulting in rupture of lens cataract (RLC), spontaneous mutation of the gene encoding DOCK 5 leads to deletion of the DHR-1 domain, which exchanges bound GDP for free GTP, which functions to bind phospholipids and assists in protein-protein interactions, while presumably acting as a guanine nucleotide exchange factor (GEF), 870 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins, DOCK 5 is a 1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FLJ21034
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDOCK5 Conjugated
Short name FITC Conjugated, DOCK5 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, dedicator on cytokinesis 5 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Cytoplasm, DOCK5 and IDBG-12661 and ENSG00000147459 and 80005, DOCK5 and IDBG-635373 and ENSBTAG00000015513 and 505572, Dock5 and IDBG-176271 and ENSMUSG00000044447 and 68813, protein binding, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0043547 and positive regulation of GTPase activity and biological process, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005488: binding and also this GO :0005515: protein binding, this GO :0005488: binding, this GO :0005515: protein binding, dedicator of cytokinesis 5
Identity 23476
Gene DOCK5
Long gene name dedicator of cytokinesis 5
Locus 8p21, 2
Discovery year 2003-11-19
Entrez gene record 80005
Pubmed identfication 12432077
RefSeq identity NM_024940
Havana BLAST/BLAT OTTHUMG00000131991

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