DOG-1/ ANO1

DOG-1/ ANO1 size: 100ug 354

Price 354

Size 100ug

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Also known as	DOG-1
Other names	Anoctamin-1, Ca2+-activated Cl- channel, Discovered on gastrointestinal stromal tumors protein 1, Oral cancer overexpressed protein 2, Transmembrane protein 16A, Tumor-amplified and overexpressed sequence 2, anoctamin 1, anoctamin-1, calcium activated chloride channel, discovered on gastrointestinal stromal tumors protein 1, oral cancer overexpressed 2, transmembrane protein 16A (eight membrane-spanning domains), tumor-amplified and overexpressed sequence 2, anoctamin-1
Category	Antibodies
Subcategory	Mnoclonal antibodies
Gene name	TMEM16A
Gene name synonims	N/A
Other gene names	ANO1, DOG1, DOG1, ORAOV2, ORAOV2, TAOS2, TAOS2, TMEM16A, TMEM16A, ANO1
Clonality	Monoclonal
Immunoglobulin isotype	kappa, IgG1
Clone	DG1/447
Host organism	Mouse (Mus musculus)
Species reactivity	Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity	94, DOG-1 is rarely expressed in other soft tissue tumors, Immunoreactivity for DOG-1 has been reported in 97, Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The overall sensitivity of DOG1 and c-kit in GIST's is nearly identical: 94, This particular antibody might cross react with speacies outside of the listed ones, c-kit signaling-driven mesenchymal tumors of the GI tract, due to appearance, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen, including all c-kit negative GIST's, may be difficult to diagnose, which, 4% vs, 7%, 8 percent of scorable GIST's, Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST's)
Purification method	N/A
Form/Appearance	N/A
Concentration	N/A
Storage and shipping	Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications:	Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA)
Gene target	1/ ANO1
Short name	DOG-1/ ANO1
Alternative name	canine-1/ ANO1
Identity	21625
Gene	ANO1
Long gene name	anoctamin 1
Synonyms gene	ORAOV2 TMEM16A
Synonyms gene name	calcium activated chloride channel , oral cancer overexpressed 2 transmembrane protein 16A anoctamin 1
Synonyms	TAOS2 FLJ10261 DOG1
Locus	11q13, 3
Discovery year	2003-10-16
GenBank acession	BC033036
Entrez gene record	55107
Pubmed identfication	15067359 18724360 24692353
RefSeq identity	NM_018043
Classification	Anoctamins
Havana BLAST/BLAT	OTTHUMG00000167204

DOG-1/ ANO1

DOG-1/ ANO1 size: 100ug 354

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