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DOK1 (Tyr398) Antibody, Cy3 Conjugated

DOK1 (Tyr398) Antibody, Cy3 Conjugated size: 0.1ml 368

Price 368
Size 0.1ml
Long name Cy3 Conjugated, DOK1 (Tyr398) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDOK1 Tyr398
SpecificityThis is a highly specific antibody against DOK1 Tyr398
ModificationPhosphorylation
Modification siteTyr398
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr398
Gene ID number1796
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs, Docking protein 2 binds p120 (RasGAP) from CML cells, It has been postulated to play a role in mitogenic signaling, It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML, Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms p62dok
Properties 1 of the DOK1 (Tyr398) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDOK1 (Tyr398) Conjugated
Short name Conjugated, DOK1 (Tyr398) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name 62kDa (downstream on tyrosine kinase 1) (Tyr398) (Antibody to), cyanine 3 coupled, docking protein 1
Alternative techniqueantibodies
Alternative to gene target 62kDa (downstream of tyrosine kinase 1), DOK1 and IDBG-57879 and ENSG00000115325 and 1796, DOK1 and IDBG-631228 and ENSBTAG00000018579 and 514962, Dok1 and IDBG-159342 and ENSMUSG00000068335 and 13448, P62DOK, nuclei, protein binding, this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005158 and insulin receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component, this GO :0005057: receptor signaling protein activity, this GO :0005057: receptor signaling protein activity and also this GO :0005158: insulin receptor binding and also this GO :0005515: protein binding, this GO :0005158: insulin receptor binding, this GO :0005515: protein binding, docking protein 1
Identity 2990
Gene DOK1
Long gene name docking protein 1
Synonyms gene name 62kD (downstream of tyrosine kinase 1) docking protein 1, 62kDa (downstream of tyrosine kinase 1) , docking protein 1
Synonyms name downstream of tyrosine kinase 1
Locus 2p13, 1
Discovery year 1997-07-25
GenBank acession U70987
Entrez gene record 1796
Pubmed identfication 9008160 9790776 15546884
RefSeq identity NM_001381
Havana BLAST/BLAT OTTHUMG00000129956

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