Name : DOK1 (Tyr398) Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN4197901610
| Long name | Cy3 Conjugated, DOK1 (Tyr398) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DOK1 Tyr398 |
| Specificity | This is a highly specific antibody against DOK1 Tyr398 |
| Modification | Phosphorylation |
| Modification site | Tyr398 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr398 |
| Gene ID number | 1796 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs, Docking protein 2 binds p120 (RasGAP) from CML cells, It has been postulated to play a role in mitogenic signaling, It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML, Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | p62dok |
| Properties | 1 of the DOK1 (Tyr398) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DOK1 (Tyr398) Conjugated |
| Short name | Conjugated, DOK1 (Tyr398) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | 62kDa (downstream on tyrosine kinase 1) (Tyr398) (Antibody to), cyanine 3 coupled, docking protein 1 |
| Alternative technique | antibodies |
| Alternative to gene target | 62kDa (downstream of tyrosine kinase 1), DOK1 and IDBG-57879 and ENSG00000115325 and 1796, DOK1 and IDBG-631228 and ENSBTAG00000018579 and 514962, Dok1 and IDBG-159342 and ENSMUSG00000068335 and 13448, P62DOK, nuclei, protein binding, this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005158 and insulin receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component, this GO :0005057: receptor signaling protein activity, this GO :0005057: receptor signaling protein activity and also this GO :0005158: insulin receptor binding and also this GO :0005515: protein binding, this GO :0005158: insulin receptor binding, this GO :0005515: protein binding, docking protein 1 |
| Identity | 2990 |
| Gene | DOK1 |
| Long gene name | docking protein 1 |
| Synonyms gene name | 62kD (downstream of tyrosine kinase 1) docking protein 1, 62kDa (downstream of tyrosine kinase 1) , docking protein 1 |
| Synonyms name | downstream of tyrosine kinase 1 |
| Locus | 2p13, 1 |
| Discovery year | 1997-07-25 |
| GenBank acession | U70987 |
| Entrez gene record | 1796 |
| Pubmed identfication | 9008160 9790776 15546884 |
| RefSeq identity | NM_001381 |
| Havana BLAST/BLAT | OTTHUMG00000129956 |