Name : DOK4 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2455125106
| Long name | DOK4 Primary Polyclonal Antibody |
| Also known as | DOK4 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DOK4 |
| Specificity | This is a highly specific antibody against DOK4 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DOK4 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Additionally, Dok-4 (Downstream of kinase-4) is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation, Expressed in a variety of tissues with highest expression in liver, Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, heart, kidney and skeletal muscle, mediate biological responses within the body, suggesting a role for Dok-4 in tumorigenesis, via this interaction, The downstream of kinase family (Dok-1-7) are members of a class of docking proteins that interact with receptor tyrosine kinases and |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DOK4_HUMAN, Downstream of tyrosine kinase 4, FLJ10488, docking protein 4 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DOK4 |
| Short name | DOK4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | DOK4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19868 |
| Gene | DOK4 |
| Long gene name | docking protein 4 |
| Synonyms | FLJ10488 |
| Locus | 16q21 |
| Discovery year | 2002-11-28 |
| GenBank acession | BC003541 |
| Entrez gene record | 55715 |
| Pubmed identfication | 10493829 |
| Classification | Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000133460 |