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DOK7 Antibody, Biotin Conjugated

DOK7 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, DOK7 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDOK7
SpecificityThis is a highly specific antibody against DOK7
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DOK7
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Based on their similarities, Dok-4/5/6 and Dok-7, Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation, Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters, Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) â, Through its interaction with muscle-specific receptor kinase (MuSK), recessively inherited disorders characterized by muscle weakness, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, which contain multiple tyrosine residues and putative SH2 binding sites, &euro, &euro, &euro, &oelig, &rdquo, The downstream of kinase family (Dok1-7) are members of a class of â, dockingâ,  proteins that include the tyrosine kinase substrates IRS-1 and Cas
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FLJ33718 FLJ39137 Dok-7
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDOK7 Conjugated
Short name Conjugated, DOK7 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, DOK7 (Antibody to)
Alternative techniqueantibodies
Identity 26594
Gene DOK7
Long gene name docking protein 7
Synonyms gene C4orf25
Synonyms gene name chromosome 4 open reading frame 25
Locus 4p16, 3
Discovery year 2006-05-22
GenBank acession AK091037
Entrez gene record 285489
Pubmed identfication 16794080
RefSeq identity NM_173660
Havana BLAST/BLAT OTTHUMG00000122087
Locus Specific Databases Leiden Muscular Dystrophy pages LRG_869

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