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Doppel/DPL Antibody, ALEXA FLUOR 350

Doppel/DPL Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, Doppel/DPL Polyclonal Antibody
Also known asAnti-Doppel/DPL PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDoppel/DPL
SpecificityThis is a highly specific antibody against Doppel/DPL
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Doppel
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen BSE in cattle, Dpl does not appear to contribute to prion disease progression, Dpl is also thought to play a role in angiogenesis, Dpl is characterized by an alpha-helical conformation, Dpl is highly expressed in adult testis and heart and is detectable in the brain of neonatal mice, Infectious PrPSc is highly expressed in the brain of animals affected by TSEs, The PRND gene locus, and Cruetzfeldt-Jacob disease in humans, and it is presented on the cell surface by a glycosylphosphatidylinositol anchor, and two N-linked oligosaccharides, but ectopic expression of Dpl is implicated in neuronal degeneration of ataxic PRP-deficient mice, encodes for the doppel protein (Dpl), including scrapie in sheep, infectious or sporadic, intramolecular disulfide bonds, lethal neurodegenerative disorders involving alterations of the prion protein (PrP), located on human chromosome 20p, specifically maturation of the blood-brain barrier, which exhibits approximately 25% sequence homology with PrP, Prion diseases or transmissible spongiform encephalopathies (TSEs) are manifested as genetic
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms DPL dJ1068H6, 4 DOPPEL PrPLP
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetDoppel/DPL
Short nameDoppel/DPL Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, Doppel/DPL (Antibody to)
Alternative techniqueantibodies
Identity 15748
Gene PRND
Long gene name prion like protein doppel
Synonyms gene name prion protein 2 (dublet)
Synonyms name prion-like protein doppel downstream prion protein-like gene
Locus 20p13
Discovery year 2001-05-30
GenBank acession AF106918
Entrez gene record 23627
Pubmed identfication 10525406 10577243
RefSeq identity NM_012409
Havana BLAST/BLAT OTTHUMG00000031789

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