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DORFIN/RNF19 Antibody

DORFIN/RNF19 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDORFIN/RNF19 Primary Polyclonal Antibody
Also known asDORFIN/RNF19 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDORFIN/RNF19
SpecificityThis is a highly specific antibody against DORFIN/RNF19
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DORFIN/RNF19
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CaSR and mutant variants of SOD-1, Dorfin functions by accepting ubiquitin in the form of a thioester from UBCH7 and UBC8 and then transferring it to the targeted substrates, Dorfin is responsible for ubiquitylating synphilin-1, Dorfin physically interacts with VCP (Valosin-containing protein) via its C-terminus, E3 ubiquitin-protein ligase, It is widely expressed with highest levels found in heart and ubiquitous expression throughout the central nervous system, RING-IBR type, This association with UBIs suggests that Dorfin plays an important role in the disease process, Together these two proteins are associated with the formation of ubiquitylated inclusions (UBIs) that characterize many neurodegenerative disorders, a protein at fault for familial ALS (amyotrophic lateral sclerosis), such as Parkinsonâ, &euro, &trade, Dorfin is a multi-pass membrane, s disease and ALS
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AA032313, DKFZP566B1346, Double ring finger protein, Double ring-finger protein, E3 ubiquitin-protein ligase RNF19A, RING finger protein 19A, RN19A_HUMAN, RNF19, RNF19A, Ring IBR ring domain containing protein Dorfin, Ring finger protein 19, UIP117, Ubce7ip2, XYbp, p38, p38 protein, Dorfin
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDORFIN/RNF19
Short nameDORFIN/RNF19 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDORFIN/RNF19 (Antibody to)
Alternative techniqueantibodies
Identity 13432
Gene RNF19A
Long gene name RBR E3 ubiquitin protein ligase , ring finger protein 19A
Synonyms gene RNF19
Synonyms gene name E3 ubiquitin protein ligase , ring finger protein 19 ring finger protein 19A ring finger protein 19A
Synonyms dorfin DKFZp566B1346
Locus 8q22, 2
Discovery year 2003-02-28
GenBank acession AB029316
Entrez gene record 25897
Pubmed identfication 11237715 10976766
RefSeq identity NM_015435
Classification Ring finger proteins RBR E3 ubiquitin ligases
Havana BLAST/BLAT OTTHUMG00000164707

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