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DORFIN/RNF19 Antibody, ALEXA FLUOR 555

DORFIN/RNF19 Antibody, ALEXA FLUOR 555 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 555 Conjugated, DORFIN/RNF19 Polyclonal Antibody
Also known asAnti-DORFIN/RNF19 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDORFIN/RNF19
SpecificityThis is a highly specific antibody against DORFIN/RNF19
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DORFIN/RNF19
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen CaSR and mutant variants of SOD-1, Dorfin functions by accepting ubiquitin in the form of a thioester from UBCH7 and UBC8 and then transferring it to the targeted substrates, Dorfin is responsible for ubiquitylating synphilin-1, Dorfin physically interacts with VCP (Valosin-containing protein) via its C-terminus, E3 ubiquitin-protein ligase, It is widely expressed with highest levels found in heart and ubiquitous expression throughout the central nervous system, RING-IBR type, This association with UBIs suggests that Dorfin plays an important role in the disease process, Together these two proteins are associated with the formation of ubiquitylated inclusions (UBIs) that characterize many neurodegenerative disorders, a protein at fault for familial ALS (amyotrophic lateral sclerosis), such as Parkinsonâ, &euro, &trade, Dorfin is a multi-pass membrane, s disease and ALS
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms dorfin DKFZp566B1346
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetDORFIN/RNF19
Short nameDORFIN/RNF19 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, DORFIN/RNF19 (Antibody to)
Alternative techniqueantibodies
Identity 13432
Gene RNF19A
Long gene name RBR E3 ubiquitin protein ligase , ring finger protein 19A
Synonyms gene RNF19
Synonyms gene name E3 ubiquitin protein ligase , ring finger protein 19 ring finger protein 19A ring finger protein 19A
Locus 8q22, 2
Discovery year 2003-02-28
GenBank acession AB029316
Entrez gene record 25897
Pubmed identfication 11237715 10976766
RefSeq identity NM_015435
Classification Ring finger proteins RBR E3 ubiquitin ligases
Havana BLAST/BLAT OTTHUMG00000164707

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