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DORFIN/RNF19 Antibody, Biotin Conjugated

DORFIN/RNF19 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, DORFIN/RNF19 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDORFIN/RNF19
SpecificityThis is a highly specific antibody against DORFIN/RNF19
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DORFIN/RNF19
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CaSR and mutant variants of SOD-1, Dorfin functions by accepting ubiquitin in the form of a thioester from UBCH7 and UBC8 and then transferring it to the targeted substrates, Dorfin is responsible for ubiquitylating synphilin-1, Dorfin physically interacts with VCP (Valosin-containing protein) via its C-terminus, E3 ubiquitin-protein ligase, It is widely expressed with highest levels found in heart and ubiquitous expression throughout the central nervous system, RING-IBR type, This association with UBIs suggests that Dorfin plays an important role in the disease process, Together these two proteins are associated with the formation of ubiquitylated inclusions (UBIs) that characterize many neurodegenerative disorders, a protein at fault for familial ALS (amyotrophic lateral sclerosis), such as Parkinsonâ, &euro, &trade, Dorfin is a multi-pass membrane, s disease and ALS
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms dorfin DKFZp566B1346
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDORFIN/RNF19 Conjugated
Short name Conjugated, DORFIN/RNF19 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, DORFIN/RNF19 (Antibody to)
Alternative techniqueantibodies
Identity 13432
Gene RNF19A
Long gene name RBR E3 ubiquitin protein ligase , ring finger protein 19A
Synonyms gene RNF19
Synonyms gene name E3 ubiquitin protein ligase , ring finger protein 19 ring finger protein 19A ring finger protein 19A
Locus 8q22, 2
Discovery year 2003-02-28
GenBank acession AB029316
Entrez gene record 25897
Pubmed identfication 11237715 10976766
RefSeq identity NM_015435
Classification Ring finger proteins RBR E3 ubiquitin ligases
Havana BLAST/BLAT OTTHUMG00000164707

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