Name : DR1 protein Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2225090907
| Long name | DR1 protein Primary Polyclonal Antibody |
| Also known as | DR1 protein PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DR1 protein |
| Specificity | This is a highly specific antibody against DR1 protein |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DR1 protein |
| Gene ID number | 10589 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | (DRAP1) to comprise the conserved eukaryotic complex, (negative cofactor 2 subunit â, Both subunits, DR1 forms a heterodimer with NC2&, DR1 localizes to the nucleus and contains an N-terminal histone fold motif, More specifically, NC2 (negative cofactor 2), NC2 activity is regulated by phosphorylation, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription, NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB, NC2&, The NC2 complex can both positively and negatively regulate transcription by RNA Pol II, Via its histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region, also known as NC2â, and DR1, are phosphorylated in vivo, is a TFIID (TATA box-binding protein)-associated protein, &circ, &circ, «, «, ), DR1, aring, aring |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DR 1, Down regulator of transcription 1, Down regulator of transcription 1 TBP binding, Down-regulator of transcription 1, Dr1, NC 2, NC2, NC2 beta, NC2-beta, NC2B_HUMAN, Negative co factor 2, Negative cofactor 2, Negative cofactor 2 beta, Negative cofactor 2-beta, Protein Dr1, TATA binding protein associated phosphoprotein, TATA-binding protein-associated phosphoprotein, Dr1 protein |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DR1 protein |
| Short name | DR1 protein Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | DR1 protein (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3017 |
| Gene | DR1 |
| Long gene name | down-regulator of transcription 1 |
| Synonyms gene name | TBP-binding (negative cofactor 2) , down-regulator of transcription 1 |
| Synonyms | NC2-BETA NC2B |
| Synonyms name | negative cofactor 2 negative cofactor 2 beta |
| Locus | 1p22, 1 |
| Discovery year | 1996-07-11 |
| GenBank acession | M97388 |
| Entrez gene record | 1810 |
| Pubmed identfication | 1339312 9040789 |
| RefSeq identity | NM_001938 |
| Classification | ATAC complex |
| Havana BLAST/BLAT | OTTHUMG00000010862 |