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DR3 Antibody (Death Receptor 3)

DR3 Antibody (Death Receptor 3) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDR3 (Death Receptor 3)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the DR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis DR3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q93038
PurityAntigen affinity
Description Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus, Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, The signal transduction of this receptor is mediated by various death domain containing adaptor proteins, This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis, This receptor is expressed preferentially in the tissues enriched in lymphocytes, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation, and it may play a role in regulating lymphocyte homeostasis, membrane bound isoforms, most of which are potentially secreted molecules, which predominantly produces full-length, The protein encoded by this gene is a member of the TNF-receptor superfamily
ImmunogenA portion of amino acids 214-242 from the human protein was used as the immunogen for this DR3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DR3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDR3 (Death Receptor 3)
Short nameDR3 Antibody (Death Receptor 3)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDR3 (Antibody to) (Death Receptor 3)
Alternative techniqueantibodies
Identity 11910
Gene TNFRSF25
Long gene name TNF receptor superfamily member 25
Synonyms gene TNFRSF12
Synonyms gene name member 12 (translocating chain-association membrane protein) tumor necrosis factor receptor superfamily, member 25 , tumor necrosis factor receptor superfamily
Synonyms DR3 TRAMP WSL-1 LARD WSL-LR DDR3 TR3 APO-3
Locus 1p36, 31
Discovery year 1998-12-04
GenBank acession U72763
Entrez gene record 8718
Pubmed identfication 9052839 8934525
RefSeq identity NM_148965
Classification Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000000831

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